2. Go to File and pull down to New... 
 
 

3. Click on the canvas size you want by setting the width, height 
    and resolution in pixels, inches, centimeters and more. 72 pixels
    per inch is good for web sites. 144 pixels works on most
    printers--you may need to test this to get a good printing size
    for your printer. Let's start by creating a new 400 X 400 pixel
    canvas, 72 pixels per inch resolution. 

The Tools Palette is where you can find standard tools:
Eye Dropper
Selection Tool
Text
Paint Bucket
Brushes

The Controls Palette contains options for the tool you select from the Tools Palette.

The Art Materials Palatte has 5 sub-palattes: 
Color
Paper
Gradient
Pattern
Nozzle

The Brushes Palette  holds different kinds of brushes. See below.

The Brushes Palette only displays 3 brushes at one time but has several more. To see the other brushes, click on the drawer pushbar (the light purple triangle) then you will see a sub-menu with more tools and controls for the current palette. You may also click the Painter and Brush variant menu to see more option. (See the picture example on the right--this displays the Brushes Palette with the Drawer open.)

To select a color, you need to selet the hue by sliding the circle around the Hue Ring, and the Saturation (brightness or dullness) and Value (darkness or lightness) by sliding the triangle insid the Color Triangle. Values go from top to bottom in the triangle, and saturation goes from left to right. Go ahead and select the color you want.

The hue circle has a small marker that shows the currently choosen hue. Click in the hue circle to select a different hue and notice how the triangle inside the hue triangle inside the hue circle changes. Once you have your hue or choice look into the triangle to further define your color.

The triangle also contains a small marker that can be moved to the three corners of the triangle and anywhere in between. The triangle defines the Saturation and Value of your selected hue. The further you move the marker to the right corner the more saturated your color will be, moving to the left reduces the saturation. Sauration expresses how much cray your color is mixed with (to determine brightness or dullness). Value goes from the top to the bottom of the triangle. Highest value (white) at the top, lowest (black) at bottom. Value defines the lightness or darkness of a color.